Laser ablation sampling provides significant benefits and capabilities
for chemical analysis. It represents one of the most promising techno
logies for direct solid sample introduction. Despite the advantages, t
here are a number of issues that should be addressed to better underst
and and utilize this technology. baser ablation itself is a complex pr
ocess and is poorly understood, fundamentally. In this paper, we descr
ibe the current achievements and limitations in order to better unders
tand and utilize laser ablation sampling for chemical analysis. Severa
l current issues related to laser ablation sampling are discussed, inc
luding calibration and optimization, fractionation, sensitivity enhanc
ements, mass loading, and particle transport. Published by Elsevier Sc
ience B.V.