Previous research has highlighted the high prevalence (30-60%) of como
rbid anxiety and mood disorders in clients with substance misuse disor
ders and, equivalently. a third of those with affective disorder repor
t a history of substance use disorder (Kessler et al., 1994; Regier et
al., 1990; Robins & Regier, 1991). This article reviews the managemen
t of such cases and identifies key issues in the assessment process, a
s well as potential avenues for treatment. Other articles have highlig
hted the increased service utilisation and the cost of care and treatm
ent of comorbidity. This article will primarily focus on the managemen
t of individual cases and will briefly refer to issues of service orga
nisation. Although antidepressant or anxiolytic pharmacotherapy may ha
ve a role in the treatment of severe disorders, the benefits of using
these medications must be balanced against the increased risk of side-
effects or adverse reactions in individuals who continue to engage in
substance misuse or who have medical complications associated with dru
g or alcohol dependency. Effective psychosocial approaches largely foc
us on brief, empirically tested manualised therapies such as cognitive
therapy (Carroll, 1998a). However, modifications are required to such
approaches to ensure that the interventions are tailored to the needs
of clients exhibiting comorbidity. The data available demonstrate som
e evidence for the benefits of structured psychological approaches, bu
t more sophisticated randomized controlled trials are required to eval
uate the efficacy of both psychological and pharmacological approaches
. (C) 1998 Elsevier Science Ltd.