A NOVEL DOUBLE ADDITION OF ISOCYANOACETAMIDE TO N-SULFONYLIMINES FOR THE SYNTHESIS OF TRISUBSTITUTED OXAZOLES

Authors
ZHOU XT LIN YR DAI LX SUN J
Citation
Xt. Zhou et al., A NOVEL DOUBLE ADDITION OF ISOCYANOACETAMIDE TO N-SULFONYLIMINES FOR THE SYNTHESIS OF TRISUBSTITUTED OXAZOLES, Tetrahedron, 54(41), 1998, pp. 12445-12456
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
41
Year of publication
1998
Pages
12445 - 12456
Database
ISI
SICI code
0040-4020(1998)54:41<12445:ANDAOI>2.0.ZU;2-1
Abstract
The reaction of isocyanoacetamide with N-sulfonylimine gives a novel d ouble addition product in the absence of acid base and catalyst to for m 2, 4-disubstituted-5-amino-1, 3-oxazole. A possible mechanism of thi s reaction is discussed. (C) 1998 Elsevier Science Ltd. All rights res erved.