DESULFURIZATION OF BIOTIN AND EPIBIOTIN SULFOXIDES WITH NICKEL BORIDE- ANALYSIS OF THE STEREOSELECTIVITY THROUGH [H-2] NMR IN A POLYPEPTIDE LIQUID-CRYSTAL

Authors
ESCALETTES F FLORENTIN D MARQUET A CANLET C COURTIEU J
Citation
F. Escalettes et al., DESULFURIZATION OF BIOTIN AND EPIBIOTIN SULFOXIDES WITH NICKEL BORIDE- ANALYSIS OF THE STEREOSELECTIVITY THROUGH [H-2] NMR IN A POLYPEPTIDE LIQUID-CRYSTAL, Tetrahedron letters, 39(41), 1998, pp. 7499-7502
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
41
Year of publication
1998
Pages
7499 - 7502
Database
ISI
SICI code
0040-4039(1998)39:41<7499:DOBAES>2.0.ZU;2-S
Abstract
Reduction of biotin or epibiotin sulfoxides with nicker boride and deu terated reagents affords as major products bideuterated dethiobiotin. Deuterium localisation by [H-2] NMR in a chiral liquid crystal allows the analysis of the stereoselectivity of the reaction (C) 1998 Elsevie r Science Ltd. All rights reserved.