VULVAR INTRAEPITHELIAL NEOPLASIA AND CARCINOMA

This report describes the classification, clinical profile, etiology, and management of high-grade squamous vulvar intraepithelial-neoplasia (VIN). Recent studies have better defined the progressive potential o f high grade VIN and the relationship of such lesions to squamous vulv ar carcinoma. The histologic classification and descriptions have unde rgone significant refinement over the past decade. The increasing use of more conservative therapeutic approaches to high grade VIN has dema nded greater expertise in clinical evaluation to ensure invasive disea se is not missed or undertreated, Copyright (C) 1998 by W.B. Saunders Company.