DNA GENETIC VACCINATION (MINIREVIEW)

An important new approach to vaccination is plasmid DNA injection in v ivo that can elicit an immune response against protein(s) encoded. Ant igen that is expressed from the in vivo transfected cells induces both humoral and cellular immune response. DNA immunization is generally a pplicable for a wide range of proteins. It can provide an organism wit h immunity against viruses, bacteria, parasites, and tumors. DNA vacci nes can overcome the disadvantages of vaccines presently used as well as provide various new vaccines that are currently not available. This minireview provides an overview of evaluated DNA vaccine candidates a gainst infectious agents and certain cancers.