The aim of this prospective study was to assess the value of laparosco
pic treatment of severe fimbrial occlusions. During a period of 52 mon
ths infertile patients with fimbrial lesions were treated by operative
laparoscopy. Only those patients requiring incision of the tubal sero
sa (salpingostomy) were included, representing the most severe lesions
. The most frequent cases, those patients requiring simple adhesiolysi
s and deagglutination of the fringes, were excluded. All tubal lesions
were documented carefully. Positive Chlamydia trachomatis (CT) serolo
gy was found in 65.7% of the patients. All the patients were followed
up for at least 2 years. Three patients lost to follow-up were defined
as failures. The global conception rate was 74.3%. The intrauterine p
regnancy rate was 51.4%, and the 'take home baby rate' was 37.1% (only
the first pregnancy being taken into account). The ectopic pregnancy
rate was 22.9%. A positive CT serology was found to have a significant
influence on the outcome. It can be concluded that the laparoscopic a
pproach provides results similar to those obtained by microsurgery for
the treatment of severe fimbrial occlusions, and represents an accept
able alternative to in-vitro fertilization (IVF) in selected cases.