B. Salle et al., PRELIMINARY-REPORT OF AN ULTRASONOGRAPHY AND COLOR DOPPLER UTERINE SCORE TO PREDICT UTERINE RECEPTIVITY IN AN IN-VITRO FERTILIZATION PROGRAM, Human reproduction (Oxford. Print), 13(6), 1998, pp. 1669-1673
A total of 96 women undergoing in-vitro fertilization (IVF) treatment
were examined by transvaginal ultrasonography with colour and pulsed D
oppler ultrasound on the 22nd day of the menstrual cycle preceding IVF
, We assessed endometrial thickness, endometrial morphology, myometria
l echogenicity, subendometrial vascularization, the uterine artery pul
satility index, protodiastolic notch and end diastolic blood flow in o
rder to define a uterine score which could be correlated with the preg
nancy rate. The overall pregnancy rate was 30.2%, and there was no dif
ference between the pregnant and non-pregnant groups with regard to an
y of the ultrasonographic and Doppler parameters when examined separat
ely. However, the uterine score was significantly higher in the pregna
nt group (15.9 +/- 2.81 versus 12.7 +/- 5.3, P = 0.002; t-test), No pr
egnancy occurred if the score was between 0 and 10, With a score of 11
-15 there was a 34.7% chance of pregnancy, and scores >16 had a 42% ch
ance of pregnancy. In conclusion, individual ultrasonographic and Dopp
ler parameters are not of sufficient accuracy to predict uterine recep
tivity, The uterine score calculated prior to IVF cycles appears to be
a useful predictor of implantation.