LIDOCAINE, QUINIDINE, AND THEOPHYLLINE BINDING TO HUMAN-MILK

Authors
BAILEY DN
Citation
Dn. Bailey, LIDOCAINE, QUINIDINE, AND THEOPHYLLINE BINDING TO HUMAN-MILK, Annals of clinical and laboratory science, 28(5), 1998, pp. 289-292
Citations number
10
Categorie Soggetti
Medical Laboratory Technology
Journal title
Annals of clinical and laboratory science → ACNP
ISSN journal
00917370
Volume
28
Issue
5
Year of publication
1998
Pages
289 - 292
Database
ISI
SICI code
0091-7370(1998)28:5<289:LQATBT>2.0.ZU;2-6
Abstract
Lidocaine, quinidine, and theophylline binding to normal pooled mature human milk was determined using equilibrium dialysis at 4 degrees C. Binding to milk was compared with binding to pooled human serum. The o bserved binding was related to the relative lipid solubility of each d rug in milk. The potential for the excretion of each drug into milk wa s also evaluated.