SMITH-FINEMAN-MYERS-SYNDROME IN APPARENTLY MONOZYGOTIC TWINS

We report on two boys, monozygotic twins born to normal and nonconsang uineous parents, presenting with an unusual facial appearance, cortica l atrophy, dolichocephaly, short stature, cleft palate, micrognathia, prominent upper central incisors, bilateral Sidney Line, minor foot de formities, unstableness in walking, early hypotonia, hyperreflexia, hy peractivity, psychomotor retardation, and severe delay in language dev elopment. These manifestations resemble those previously described in the Smith-Fineman-Myers syndrome. (C) 1998 Wiley-Liss, Inc.