Study Design. Four combinations of cable-graft-screw fixation at C1-C2
were compared biomechanically in vitro using nondestructive flexibili
ty testing. Each specimen was instrumented successively using each fix
ation combination. Objectives. To determine the relative amounts of mo
vement at C1-C2 after instrumentation with Various combinations of one
or two transarticular screws and a posterior cable-secured graft. Als
o to determine the role of each component of the construct in resistin
g different types of loading. Summary of Background Data, Spinal stiff
ness increases after instrumentation with two transarticular screws pl
us a posterior wire-graft compared with a wire-graft alone. Other C1-C
2 cable-graft-screw combinations have not been tested.Methods. Eight h
uman cadaveric occiput-C3 specimens were loaded nondestructively with
pure moments, and nonconstrained motion at C1-C2 was measured. The ins
trumented states tested were a C1-C2 interposition graft attached with
multistranded cable; a cable-graft plus one transarticular screw; two
transarticular screws atone; and a cable-graft plus two transarticula
r screws. Results. The transarticular screws prevented lateral bending
and axial rotation better than the posterior cable-graft. The cable-g
raft prevented flexion and extension better than the screws. increasin
g the number of fixation points often significantly decreased the rota
tion and translation (paired t test; P < 0.05). Axes of rotation shift
ed from their normal location toward the hardware.Conclusions. It is m
echanically advantageous to include as many fixation points as possibl
e when atlantoaxial instability is treated surgically.