PREPARATIVE ENANTIOSEPARATION ON POLYSACCHARIDE PHASE USING MICROPOROUS SILICA AS A SUPPORT

Authors
TIRITAN ME CASS QB DELALAMO A MATLIN SA GRIEB SJ
Citation
Me. Tiritan et al., PREPARATIVE ENANTIOSEPARATION ON POLYSACCHARIDE PHASE USING MICROPOROUS SILICA AS A SUPPORT, Chirality, 10(7), 1998, pp. 573-577
Citations number
17
Categorie Soggetti
Chemistry Medicinal","Chemistry Analytical","Chemistry Inorganic & Nuclear","Pharmacology & Pharmacy
Journal title
Chirality → ACNP
ISSN journal
08990042
Volume
10
Issue
7
Year of publication
1998
Pages
573 - 577
Database
ISI
SICI code
0899-0042(1998)10:7<573:PEOPPU>2.0.ZU;2-H
Abstract
The preparative enantiomeric resolutions of hexahelicen-7-yl acetic ac id methyl ester and two sulphoxides were performed on cellulose tris(3 ,5-dimethylphenylcarbamate) coated onto aminopropylated 5-mu m silica with 120-Angstrom diameter pore. High enantiomeric purity was obtained for both enantiomers. The enantioselectivity of the amylose tris (3, 5-dimethylphenylcarbamate), cellule se and amylose tris (phenylcarbama te) phases for the hexahelicen-7-yl acetic acid derivative were also i nvestigated. (C) 1998 Wiley-Liss, Inc.