The importance of postoperative infections depends on the frequency wi
th which infection occurs as well as on the additional cost per patien
t with infection. For example, in our hospital the additional cost per
patient with infection after hernia repair was $600, compared with $2
,106 per patient with infection after colonic surgery. However, the to
tal excess cost per year was similar for hernia surgery ($44,800) and
colon surgery ($48,440). The reason is that hernia surgery is much mor
e common than colon surgery. It is a general principle of clinical aud
it that the importance of problems should be defined by their frequenc
y as well as their individual severity. A third important consideratio
n is the Likelihood that the problem can be corrected. Undue attention
has been given to the health resource costs of postoperative infectio
n at the expense of information about the intangible costs to the pati
ent (these are nonfinancial costs such as pain and disability), Health
resource costs are very dependent on medical practice variation, and
comparative studies between countries reveal marked differences in the
way that apparently similar infections are managed. Moreover, compreh
ensive audit of infection-control management often reveals wasteful pr
actice, e.g, antibiotic treatment of patients who do not in fact have
infection. Audit of postoperative infection should focus on eliminatin
g wasteful practice (e.g., prophylactic antibiotics continuing > 24 hr
s after surgery) as well as on reducing postoperative infection rates.