In the present work, we studied the propagation of solitary waves in a
prestressed thick walled elastic tube filled with an incompressible i
nviscid fluid. The effects of wall inertia and shear deformation are t
aken into account in determining the inner pressure-inner cross-sectio
nal area relation. Using the reductive perturbation technique, the pro
pagation of weakly nonlinear waves in the long wave approximation is i
nvestigated and the Korteweg-de Vries equation is obtained as the evol
ution equation. Due to dependence of the coefficients of the governing
Korteweg-de Vries equation on the initial deformation, the material p
arameters and the thickness ratio, it is observed that the solution pr
ofile changes with these parameters. The numerical calculations indica
te that for engineering materials (small alpha) the wave profile gets
steepened with increasing thickness ratio, whereas for soft biological
tissues the wave profile is not so sensitive to the thickness ratio b
ut it is quite sensitive to the material nonlinearity characterized by
the coefficient alpha. This shows that for biological tissues the mat
erial nonlinearity is more important than the geometrical nonlinearity
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