N. Colacurci et al., TIME LENGTH OF NEGATIVIZATION OF HCG SERUM VALUES AFTER EITHER SURGICAL OR MEDICAL-TREATMENT OF ECTOPIC PREGNANCY, Panminerva Medica, 40(3), 1998, pp. 223-225
Objective. The aim of this study was to compare the time length until
the human chorionic gonadotropin titer became negative after medical o
r surgical treatment of ectopic pregnancy. Experimental design. Prospe
ctive, randomized study. Participants and interventions. We compared t
ime to resolution in 30 cases of tubal pregnancies successfully treate
d, 15 underwent laparoscopic linear salpingostomy (group 1) and 15 med
ical treatment with single-ose methotrexate (group 2), The patients of
both groups had no meaningful differences of age, gestational age and
human chorionic gonadotropin mean values. Measures. During the follow
-up human chorionic gonadotropin serum values were obtained every two
days until the titer was negative. Results, The time to resolution was
33.6 +/- 6.6 days in group 1, 31.5 +/- 7.8 in group 2 with no statist
ically meaningful differences, Conclusion. The data, comparable with r
esults obtained by laparoscopic treatment, suggest that human chorioni
c gonadotropin value becomes negative independently of type of treatme
nt and residual trophoblast.