M. Lompo et al., THE TOPICAL ANTIINFLAMMATORY EFFECT OF CHLOROFORM EXTRACT FROM KHAYA-SENEGALENSIS STEM BARKS, PTR. Phytotherapy research, 12(6), 1998, pp. 448-450
The croton oil-induced mice ear oedema test was used to study the topi
cal antiinflammatory effects of petroleum ether and chloroform extract
s of Khaya senegalensis stern barks, It was found that these fractions
exhibited dose-dependent inhibitory effects. The chloroform extract a
ctivity was closely related to that of indomethacin used as standard,
was more active than the petroleum ether extract and played a pivotal
role in the topical antiinflammatory effect of Khaya senegalensis stem
barks, (C) 1998 John Wiley SL Sons, Ltd.