SCALE-UP OF AN INTERMOLECULAR BARBIER REACTION

Authors
ENNIS DS LATHBURY DC WANDERS A WATTS D
Citation
Ds. Ennis et al., SCALE-UP OF AN INTERMOLECULAR BARBIER REACTION, Organic process research & development, 2(5), 1998, pp. 287-289
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Organic process research & development → ACNP
ISSN journal
10836160
Volume
2
Issue
5
Year of publication
1998
Pages
287 - 289
Database
ISI
SICI code
1083-6160(1998)2:5<287:SOAIBR>2.0.ZU;2-C
Abstract
Addition of n-BuLi to a mixture of ketone (2) and 1,4-diiodobenzene pr ovides access to alcohol (1) in high yield. This procedure has success fully been used on molar scale.