Gp. Joshi et al., EFFECTS OF INTRAARTICULAR MORPHINE ON ANALGESIC REQUIREMENTS AFTER ANTERIOR CRUCIATE LIGAMENT REPAIR, Regional anesthesia, 18(4), 1993, pp. 254-257
Background and Objectives. Intraarticular morphine has been shown to p
rovide postoperative pain relief after knee arthroscopy. The analgesia
results from local action within the knee joint. This study was condu
cted to assess the efficacy of intraarticular morphine as a treatment
for postoperative pain after anterior cruciate ligament repair. Method
s. A randomized double blind-study was conducted in patients undergoin
g elective anterior cruciate ligament repair. Patients in the study gr
oup (n = 10) received intraarticularly 5 mg of morphine in a 25 ml dil
ution. Those in the control group (n = 10) received 25 ml of saline by
the same route. Intravenous morphine with patient-controlled analgesi
a was used in the postoperative period in both the groups. Visual anal
og scores were recorded at 1, 2, 4, 8, and 24 hours after the operatio
n. The amount of morphine used over the 24-hour postoperative period w
as documented. Results. The total consumption of morphine over the 24-
hour period was significantly lower (p < 0.01) in the study group comp
ared to the control group. The postoperative pain scores were lower in
the study group throughout the study period, but this did not reach s
tatistical significance. Conclusions. Intraarticular morphine reduces
analgesic requirements after anterior cruciate ligament repair and is
an effective method of providing postoperative analgesia.