IMPROVED GLYCEMIC CONTROL IN INTENSIVELY TREATED TYPE-1 DIABETIC-PATIENTS USING BLOOD-GLUCOSE METERS WITH STORAGE CAPABILITY AND COMPUTER-ASSISTED ANALYSES

OBJECTIVE - To determine the effect on glycemic control in intensively treated type 1 diabetic patients using a blood glucose meter with sto rage capability and computer-assisted analyses. RESEARCH DESIGN AND ME THODS - Glycemic control was assessed in 22 intensively treated adults with type 1 diabetes for 12 months while using a meter without memory followed by 12 months while using a meter with memory Log books were used to assist patients in managing aspects of the diabetes treatment plan during the first 12-month period, and computer-assisted analyses were used when the meter with memory was used. GHb levels were measure d monthly throughout the 24 months of observation. RESULTS - The mean GHb level averaged across all patients during the period of memory met er use (6.4%) was significantly lower than that during the period of m eter use without memory (6.9%) (P = 0.0004). The change in GHb levels from each period-specific baseline level occurred at significantly dif ferent slopes (P = 0.046) when adjusted for baseline GHb level. In add ition, the downward trend in GHb level was greater in those patients w ho increased the frequency of testing the most (r = -0.54, P = 0.01). CONCLUSIONS - Use of a meter with memory in conjunction with computer- generated analyses of stored blood glucose test results can lead to im proved glycemic control when used by a group of intensively treated ad ult diabetic patients. Improvement in glycemic control was related to frequency of blood glucose testing.