LANTHANIDE BINUCLEAR MACROCYCLIC COMPLEXES AS SYNTHETIC ENZYMES FOR THE CLEAVAGE OF DNA

Authors
ZHU B ZHAO DQ NI JZ YING D HUANG BQ WANG ZL
Citation
B. Zhu et al., LANTHANIDE BINUCLEAR MACROCYCLIC COMPLEXES AS SYNTHETIC ENZYMES FOR THE CLEAVAGE OF DNA, Journal of molecular catalysis. A, Chemical, 135(1), 1998, pp. 107-110
Citations number
18
Categorie Soggetti
Chemistry Physical
Journal title
Journal of molecular catalysis. A, Chemical → ACNP
ISSN journal
13811169
Volume
135
Issue
1
Year of publication
1998
Pages
107 - 110
Database
ISI
SICI code
1381-1169(1998)135:1<107:LBMCAS>2.0.ZU;2-I
Abstract
Lanthanide binuclear complexes can accelerate the cleavage of pUC19 pl asmid DNA, yielding predominantly linear form. The saturation kinetics of the cleavage of pUC19 was studied. The observed rates with lanthan ide binuclear complexes showed the expected increase with the catalyst concentration. The rate of cleavage is greater than that of lanthanid e ions alone. (C) 1998 Elsevier Science B.V. All rights reserved.