PRODUCTION OF [C-14]-6-PENTYL-2-PYRONE IN LIQUID CULTURES OF TRICHODERMA-HARZIANUM

C-14-Radiolabeled 6-pentyl-2-pyrone (6PP), a naturally occurring compo und with commercially important fragrance and antimicrobial properties , was produced by Trichoderma harzianum Rifai grown in liquid cultures containing D-[U-(14)G]glucose in admixture with unlabeled D-glucose a s the primary carbon source. Approximately 1.2% of the glucose consume d was converted to 6PP. Its specific incorporation rate, 5.6 x 10(5) B q/mmol, was similar to 83% of the theoretical yield if glucose was the sole carbon source.