BACKGROUND: We report two cases of rheumatism associated with hyperthy
roidism. In both cases, arthralgia totally regressed after thyroid tre
atment. REPORTS: Two 79-year-old and 59-year-old women developed manif
estations of polymyalgia rheumatica and psoriasis arthritis respective
ly. Corticosteroid therapy was ineffective and followed by manifestati
ons of hyperthyroidism. The first patient was treated with carbimazole
and the second with thyroidectomy. Once the hyperthyroidism was contr
olled, both patients experienced a dramatically rapid cure of their ar
thralgias. DISCUSSION: Scalpulo-humeral periarthritis is the main arti
cular complication of hyperthyroidism. True manifestations of ''thyrot
oxicosis rheumatism'' are unusual and may be [inked with a direct toxi
city of the thyroid hormones on joint cartilage or with an autoimmune
manifestation of hyperthyroidism.