We describe ureteral diverticula in two dogs and briefly review the re
lated literature. The diagnosis of this condition is radiographic and
based on the excretory urographic observation of multiple ureteral out
pouchings. Pathologically, ureteral transitional cell hyperplasia and
mucinous metaplasia result in submucosal proliferation of the urotheli
um and the formation of crypts and small cysts. Ureteral diverticulosi
s in humans is associated with an increased risk of urothelial maligna
ncies, such as transitional cell carcinoma of the urinary bladder. Cli
nically, both dogs were older, small breed neutered females. Both had
a history of chronic urinary obstruction. One dog died during surgery
to remove an adrenal mass, and the other was euthanized at the owner's
request because of an inoperable bladder neoplasm. Histopathologic di
agnosis of ureteral lesions confirmed the radiographic diagnosis of ur
eteral diverticula in both dogs.