MECHANOCHEMICAL COMPLEXATION BETWEEN DEOXYCHOLIC-ACID AND SALICYLIC-ACID

A complex between deoxycholic acid (DCA) and salicylic acid (SA) was p repared by grinding and coprecipitation methods. The resultant complex was characterized by means of powder X-ray diffractometry, IR spectro scopy and thermal analysis. The stoichiometry (DCA:SA 1:1) of the comp lex obtained by grinding was identical to that obtained by coprecipita tion. The powder X-ray diffraction pattern of the DCA-SA complex diffe red from the typical pattern of DCA-guest complexes such as DCA-campho r and DCA-phenanthrene complexes. IR spectra suggested that a differen t kind of hydrogen bonding was formed in the crystal of the DCA-SA com plex, compared with the other DCA-guest complexes. This was in good ag reement with data from the crystal structure.