Gj. Prescott et al., URBAN AIR-POLLUTION AND CARDIOPULMONARY ILL HEALTH - A 14.5-YEAR TIME-SERIES STUDY, Occupational and environmental medicine, 55(10), 1998, pp. 697-704
Objectives-To examine possible associations between daily concentratio
ns of urban air pollutants and hospital emergency admissions and morta
lity due to cardiac and pulmonary disease. Methods-A time series study
was conducted in the City of Edinburgh, which has a population of abo
ut 450000. Poisson log linear regression models were used to investiga
te the relation of the daily event rate with daily air pollution conce
ntrations of sulphur dioxide (SO2) and black smoke from 1981 to 1995,
and of nitrogen dioxide (NO2), ozone (O-3), carbon monoxide (CO), and
particulate matter (PM10) from 1992 to 1995. Adjustments were made for
seasonal and weekday variation, daily temperature, and wind speed. Re
sults-The most significant findings were positive associations over th
e period 1981-95 between black smoke as a mean of the previous three d
ays and daily all cause mortality in people aged greater than or equal
to 65, and respiratory mortality also in this age group (3.9% increas
e in mortality for a 10 mu g/m(3) increment in black smoke). For hospi
tal emergency admissions between 1992 and 1995 the two most significan
t findings (p<0.05) were for cardiovascular admissions of people aged
greater than or equal to 65 which showed a positive association with P
M10 as a mean of the 3 previous days, and a negative association with
O-3 as a mean of the previous three days. Analyses of outcomes based o
n linkage with previous cardiorespiratory emergency admissions did not
show substantially different results. Conclusion-These data suggest t
hat in the City of Edinburgh, after correction for confounders, there
was a small but significant association between concentrations of blac
k smoke and respiratory mortality in the older age group, probably att
ributable to higher pollution levels in the early part of the study pe
riod. There were also generally weak and variable associations between
day to day changes in concentrations of urban air pollutants at a sin
gle central point and emergency hospital admission rates from cardiac
and respiratory disease.