A. Agli et al., ROLE OF THE PLASMA AND ERYTHROCYTES IN VENOARTERIAL PORTAL CHANGES DURING POST PRANDIAL STATE IN THE RAT, Archives of physiology and biochemistry, 106(1), 1998, pp. 12-18
The determination of plasma and whole blood free amino acid concentrat
ions in arterial and portal venous blood during post prandial state in
the rat was used to estimate the role of the erythrocytes in amino ac
id exchanges. The erythrocyte contents were calculated from plasma, wh
ole blood concentrations and the hematocrit. The veno-arterial concent
ration differences in plasma were significant for all amino acids exce
pt a-aminobutyrate and ornithine whereas in the erythrocytes only 8 am
ino acids exhibit significant differences (ASP, ALA, VAL, MET, ILE, LE
U, TYR, PHE). For 6 amino acids, a significant correlation between the
plasma and the erythrocyte concentration has been found (VAL, ILE, LE
U, TYR, PHE, HIS). These data suggest that in vivo during the time of
contact between blood and organ tissues, some amino acids but not all
are significantly taken up by the erythrocytes. Thus, it may be conclu
ded that erythrocyte amino acid blood transport in arterio-venous port
al exchanges, concerns particularly tyrosine and essential amino acids
. The erythrocyte amino acid transport represents quantitatively about
20 per cent of the total blood transport.