A knowledge of the complications of parenteral nutrition is inherent i
n the design of any monitoring system. In the initial stages of therap
y, the complications are usually of electrolyte imbalance. It must als
o be appreciated that the provision of nutrition to severely malnouris
hed patients will expose underlying deficiencies, particularly of phos
phates and trace elements. In long-term parenteral nutrition, the comp
lications can be broadly divided into those associated with the line a
nd metabolic complications. The line complications include: line block
age, sepsis, and pulmonary embolism. The most important metabolic comp
lication is undoubtedly liver cholestasis, which may be associated wit
h recurrent episodes of sepsis. Any department undertaking long-term p
arenteral nutrition should have an active nutrition team to avoid comp
lications and audit outcome. (C) Elsevier Science Inc. 1998.