Fifteen patients with the loin pain and haematuria syndrome (LPH) were
compared with 10 patients with complicated renal stone disease referr
ed to the same tertiary centre and matched for age, sex and duration o
f illness. LPH patients had a history of three times more medically un
explained somatic symptoms other than loin pain (p<0.01) and a higher
proportion took analgesics regularly (p<0.01). The onset of pain was a
ssociated with an adverse psychologically important life-event in eigh
t of the LPH patients but in none of the controls (p<0.02). LPH patien
ts more frequently recalled serious parental illness and disability in
childhood (p<0.001) than controls, and a higher proportion felt respo
nsible for causing or alleviating parental illness or distress (p<0.05
). LPH subjects scored higher in the 'paternal care' dimension of the
Parental Bonding Instrument (p<0.05). No difference was found between
EPH patients and controls in terms of current depression and anxiety b
ut both groups exhibited high rates of lifetime depression. LPH patien
ts expressed lower levels of anger and hostility (p< 0.002) than did c
ontrols. Our observations suggest that psychological factors are of ma
jor importance in the aetiology of LPH, which may represent a type of
somatoform pain disorder.