UNUSUAL GASTRIC POLYP SHOWING SUBMUCOSAL PROLIFERATION OF GLANDS - CASE-REPORT AND LITERATURE-REVIEW

We report an unusual pedunculated polyp in the stomach in a 41-year-ol d woman. She was hospitalized because of epigastric discomfort. Endosc opy revealed a polyp with a long stalk in the fundus of the stomach. T he polypectomyzed polyp measured 23 x 18 x 9 mm and was characterized by submucosal proliferation of glands and cystic dilatation. The surfa ce of the polyp was covered with gastric mucosa of fundic or pyloric g land type. The glandular structures consisted of various types of lini ng cells, including pyloric or mucous-neck cell type, surface mucous ( foveolar) cell type, parietal-like cells, and somatostatin-positive ce lls. The submucosal glandular or cystic elements were connected with t he overlying gastric mucosa through a defect of the muscularis mucosa, suggesting that this polyp may have been formed by the heterotopic in verted downgrowth of mucous glands into the submucosa. We discuss the histogenesis of this rare polyp and present a review of the literature .