A NEW ROUTE TO FUNCTIONALIZED PI-ALLYLTRICARBONYLIRON LACTAM COMPLEXES FROM AZIRIDINES AND THEIR USE IN STEREOSELECTIVE SYNTHESIS AND OXIDATIVE CONVERSION TO BETA-LACTAMS

Authors
LEY SV MIDDLETON B
Citation
Sv. Ley et B. Middleton, A NEW ROUTE TO FUNCTIONALIZED PI-ALLYLTRICARBONYLIRON LACTAM COMPLEXES FROM AZIRIDINES AND THEIR USE IN STEREOSELECTIVE SYNTHESIS AND OXIDATIVE CONVERSION TO BETA-LACTAMS, Chemical communications, (18), 1998, pp. 1995-1996
Citations number
17
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
18
Year of publication
1998
Pages
1995 - 1996
Database
ISI
SICI code
1359-7345(1998):18<1995:ANRTFP>2.0.ZU;2-B
Abstract
Aziridinyl enones can be converted in good yield into pi-allyltricarbo nyliron lactam complexes bearing ketone functionality in the side chai n; addition of a variety of nucleophiles into the side chains of these complexes proceeds in good yield and excellent (> 95%) de to afford s econdary and tertiary alcohols which on treatment with trimethylamine N-oxide form the corresponding beta-lactams in good yield.