Objective: To explore the differential outcome of schizophrenia in dev
eloped and developing countries. The 15-year outcome of patients with
schizophrenia in Hong Kong is reported. Method: In a 15-year retrospec
tive outcome study, 100 patients with first-onset schizophrenia in 197
7-1978 were randomly selected for outcome assessment from a pool of 79
7 patient files. The patterns of outcome were assessed by the same set
of instruments and methodology as in other centres, since Hong Kong i
s 1 of the World Health Organization (WHO) centres for the Internation
al Study of Schizophrenia (ISoS). Results: Nineteen subjects were untr
aceable, and 10 subjects committed suicide. More than one-half of the
subjects had a good symptomatic outcome, while about 20% of the subjec
ts were rated as having a good psychosocial adjustment. Over the entir
e 15-year period, 96% of the subjects were maintained on medications,
and 79% were living with family members. Conclusion: Despite Hong Kong
's developed economy, its schizophrenia outcome is similar to that in
developing countries. The existence of good family support and active
follow-up treatment may be important contributory factors to better ou
tcome.