Carbohydrate consumption is thought to attenuate symptoms of tobacco w
ithdrawal, but direct evidence for this idea does not exist. Using a 2
x 2 (smoking/smoking deprived x sucrose/placebo) factorial design, we
examined in 67 women whether sucrose would decrease acute withdrawal
symptoms observed after 12 h of tobacco abstinence. Sucrose decreased
tobacco abstinence-induced drowsiness and anxiety and preference for f
oods high in carbohydrate and fat content. Sucrose, however, had no ef
fect on several other acute withdrawal symptoms, including restlessnes
s, irritability and concentration difficulties. These results provide
modest support for the idea that increased carbohydrate intake during
tobacco withdrawal reduces certain withdrawal symptoms even after only
12 h of abstinence.