EFFECTS OF A TIME-VARYING STRONG MAGNETIC-FIELD ON TRANSIENT INCREASEIN CYTOSOLIC-FREE CA2+ INDUCED BY BRADYKININ IN CULTURED BOVINE ADRENAL CHROMAFFIN CELLS

Authors
IKEHARA T PARK KH HOUCHI H YAMAGUCHI H HOSOKAWA K SHONO M MINAKUCHI K TAMAKI T KINOUCHI Y YOSHIZAKI K MIYAMOTO H
Citation
T. Ikehara et al., EFFECTS OF A TIME-VARYING STRONG MAGNETIC-FIELD ON TRANSIENT INCREASEIN CYTOSOLIC-FREE CA2+ INDUCED BY BRADYKININ IN CULTURED BOVINE ADRENAL CHROMAFFIN CELLS, FEBS letters, 435(2-3), 1998, pp. 229-232
Citations number
18
Categorie Soggetti
Biology,"Cell Biology",Biophysics
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
435
Issue
2-3
Year of publication
1998
Pages
229 - 232
Database
ISI
SICI code
0014-5793(1998)435:2-3<229:EOATSM>2.0.ZU;2-P
Abstract
We tested the effects of exposure to a time-varying magnetic field cha nging between 0.07 and 1.7 T at an interval of 3 s on transient increa se in intracellular Ca2+ stimulated by bradykinin in bovine adrenal ch romaffin cells. Addition of bradykinin induced the increase in intrace llular Ca2+ within a few minutes. The exposure to the magnetic field p erfectly suppressed the increase in intracellular Ca2+ in Ca2+-free me dium, The inhibition occurred for 15 min when the maximum magnetic flu x density was more than 1.4 T, These results suggest that the exposure inhibits Ca2+ release from intracellular Ca2+ stores,(C) 1998 Federat ion of European Biochemical Societies.