NEUROENDOCRINE-IMMUNE INTERACTIONS IN THE NEONATE

Cytokine responses to lipopolysaccharides in neuroendocrine tissues ar e age- and tissue-dependent in neonatal pigs. Developmental difference s in serum and tissue-specific responses are not necessarily equivalen t. Lower levels of cytokine gene expression in neuroendocrine tissues of early neonates potentially could influence neuroendocrine and immun e responses to infection. The Limited information on neuroendocrine-im mune responses and interactions in neonatal farm animals presents sign ificant challenges, as well as opportunities for new discoveries and i mprovements of livestock production. (C) Elsevier Science Inc. 1998