D. Holst et al., INTRATHECAL LOCAL-ANESTHETIC DISTRIBUTION WITH THE NEW SPINOCATH CATHETER, REGIONAL ANESTHESIA AND PAIN MEDICINE, 23(5), 1998, pp. 463-468
Background and Objectives. Microcatheters have been linked in some cas
es to the development of cauda equina syndrome, which may be further t
raced to the maldistribution of the local anesthetic. A long injection
time via the microcatheters contributes to the inadequate mixing. Wit
h the new Spinocath catheter, considerably shorter injection times can
be achieved due to larger internal size. This study examined whether
this leads to more homogeneous intrathecal distribution without causin
g greater trauma to the dura. Methods. In an in vitro model of the spi
nal canal, the distribution of hyperbaric and isobaric 0.5% bupivacain
e (2.5 mL) as well as 5% lidocaine (2.5 mL) was examined after injecti
on via the 28-gauge CoSpan catheter (Kendall, Healthcare, Mansfield, M
A), the 22-gauge Spinocath catheter (Braun, Melsungen, Germany), and a
29-gauge Quincke needle (Becton Dickinson, Rutherford, NJ). The local
anesthetic concentration in the vertebral interspaces T12-L1 to L5-S1
was measured via gas chromatography 3 and 10 minutes after injection.
Ln addition, the morphologic puncture characteristics of human dura w
ere examined with the halftone electron microscope, after puncture wit
h the catheters and needle. Results. After injection through the 28-ga
uge CoSpan catheter, caudal segments of the spinal canal showed peak c
oncentrations up to a maximum of 1,147 mu g/mL bupivacaine or 8.5 mg/m
L lidocaine with hyperbaric solutions, which did not decrease over the
10 minutes of measurement. After injection through the Spinocath cath
eter, there was a homogeneous distribution with data peaks of approxim
ately 350 mu g/mL bupivacaine or 4.2 mg/mL lidocaine similar to the da
ta found after injection through the spinal needle. Conclusions. The n
ew Spinocath catheter allows a better mixing of the local anesthetic w
ith the cerebrospinal fluid. Because of significantly shortened inject
ion times, hyperbaric solutions also show a more homogeneous distribut
ion. Although the Spinocath catheter has a larger inner diameter than
the other microcatheters, it appeared to cause less trauma to the dura
.