Bj. Larocque et al., PROSPECTIVE VALIDATION OF A POINT SCORE SYSTEM FOR PREDICTING BLOOD-TRANSFUSION FOLLOWING HIP OR KNEE REPLACEMENT, Transfusion, 38(10), 1998, pp. 932-937
BACKGROUND: The purpose of this study was to validate a previously pub
lished point score system for predicting the likelihood of a postopera
tive blood transfusion following hip or knee replacement. STUDY DESIGN
AND METHODS: Data were collected prospectively on 460 sequential pati
ents undergoing elective hip and knee replacement at two academic hosp
itals. Blood transfusion frequency was determined for patients in each
of the four risk strata, as defined by the point score system. The ac
curacy of the system was validated by calculating the area under the r
eceiver operating characteristic (ROC) curve for each site. Data were
then combined and inappropriate blood transfusions were eliminated, by
using the American College of Physicians guidelines. The frequencies
of blood transfusion within each strata were recalculated along with a
n ROC curve. RESULTS: The point score system accurately predicted the
likelihood of Mood transfusion at both hospitals, despite marked diffe
rences in overall transfusion frequencies. The calculated areas under
the ROC curves were 0.78 and 0.79 for the two sites. The point score s
ystem also proved valid when only appropriate blood transfusions were
considered, with a calculated area under the ROC curve of 0.74. CONCLU
SION: The point score system can accurately predict the likelihood of
postoperative blood transfusion following hip or knee replacement. Suc
h a system can be used to target high-risk patients for preoperative a
utologous blood donation.