G. Lock et al., AIR OESOPHAGOGRAM - A FREQUENT, BUT NOT A SPECIFIC SIGN OF ESOPHAGEALINVOLVEMENT IN CONNECTIVE-TISSUE DISEASES, British journal of rheumatology (Print), 37(9), 1998, pp. 1011-1014
Objective. This study investigates the role of the air oesophagogram i
n conventional chest X-rays for the diagnosis of oesophageal dysmotili
ty in patients with connective tissue diseases. Methods. Fifty-one pat
ients with connective tissue diseases were studied by oesophageal mano
metry and lateral and posterior-anterior chest X-rays. The presence or
absence of oesophageal air on chest X-rays were evaluated separately
in the upper, middle and distal segment of the oesophagus. Forty-seven
chest X-rays of patients without connective tissue diseases, who had
undergone manometry for the evaluation of oesophagus-related symptoms
and who had normal oesophageal function, were analysed as a control. R
esults. A total of 23/51 patients with connective tissue diseases show
ed oesophageal dysfunction in manometry; 16/51 patients (31%) had air
in two or more oesophageal segments on the lateral chest X-ray. There
was a significant association of manometrically proven oesophageal dys
motility and air in two or three oesophageal segments (P < 0.05; sensi
tivity 48%, specificity 82%). However, the prevalence of an air oesoph
agogram showed no significant difference between patients with connect
ive tissue diseases and the control group (10/47; 21%).Conclusion. The
radiological sign of an air oesophagogram is neither sensitive nor sp
ecific enough to omit oesophageal motility studies in patients with co
nnective tissue diseases.