Se. Parker et al., EVALUATION OF THE IMPACT OF NON-INPATIENT IV ANTIBIOTIC-TREATMENT FORACUTE INFECTIONS ON THE HOSPITAL, PRIMARY-CARE SERVICES AND THE PATIENT, Journal of antimicrobial chemotherapy, 42(3), 1998, pp. 373-380
The aim of this study was to assess the feasibility of providing iv an
tibiotic therapy outside hospital. The main outcome measures were the
direct costs of providing iv antibiotic therapy in the community compa
red with standard hospital treatment and the perceptions of patients a
nd General Practitioners (GPs). A total of 29 patients entered the stu
dy, of whom 15 received teicoplanin and 14 ceftriaxone. The costs of d
rugs exceeded the cost of the estimated alternative treatments (median
pound 208 and pound 126 respectively) and this was only partially com
pensated for by a small reduction in costs of consumables. The staff t
ime required to train patients was compensated for by savings in drug
preparation and administration. Sensitivity analysis showed that these
conclusions were sensitive to drug and patient selection, and that tr
eatment of skin and soft tissue infections outside hospital with ceftr
iaxone was likely to have similar variable costs to treatment in hospi
tal with drugs such as flucloxacillin. Non-inpatient iv (NIPIV) therap
y was estimated to save a total of 532 bed days in the year of the stu
dy. Patients strongly preferred non-inpatient treatment to hospital tr
eatment. GPs identified a number of potential disadvantages, mainly co
ncerning safety and lack of support for patients at home. Following th
e study a strategy for development of NIPIV services in Tayside has be
en developed with local GPs and a plan has been agreed for funding a c
ommunity liaison nurse based on the impact of NIPIV therapy on future
bed requirements in Dundee Teaching Hospitals Trust.