PROTEIN INTERACTIONS IMPLICATED IN NEUROTRANSMITTER RELEASE

Authors
ELFAR O OCONNOR V DRESBACH T PELLEGRINI L DEBELLO W SCHWEIZER F AUGUSTINE G HEUSS C SCHAFER T CHARLTON MP BETZ H
Citation
O. Elfar et al., PROTEIN INTERACTIONS IMPLICATED IN NEUROTRANSMITTER RELEASE, J PHYSL-PAR, 92(2), 1998, pp. 129-133
Citations number
26
Categorie Soggetti
Physiology,Neurosciences
Journal title
JOURNAL OF PHYSIOLOGY-PARIS
ISSN journal
09284257 → ACNP
Volume
92
Issue
2
Year of publication
1998
Pages
129 - 133
Database
ISI
SICI code
0928-4257(1998)92:2<129:PIIINR>2.0.ZU;2-K
Abstract
Biochemical evidence indicates that the exocytotic release of neurotra nsmitters involves both evolutionary conserved membrane proteins, the SNAREs, as well as ubiquitous cytosolic fusion proteins, NSF and SNAPs . We have analyzed the biochemical properties and the physiological ef fects of these proteins. Our data suggest models how NSE SNAPs and SNA REs may function in neurotransmitter exocytosis. ((C) Elsevier, Paris) .