This paper describes a methodology for representing clinical practice
guidelines and facilitating their introduction into the medical routin
e. Since this methodology can be exploited in a www environment, it ca
n represent the basis for sharing clinical guidelines both between dif
ferent institutions and between human and software agents cooperating
within a clinical context. In addition, the proposed guideline formali
zation is intended to deal with patient and organization preferences.
This goal is achieved by augmenting the guideline with decision-analyt
ic models and by linking the guideline with an organizational model of
the clinical setting. The designed framework allows guideline develop
ment, tailoring and implementation, real-time access to the guideline
prescriptions and guideline validation. (C) 1998 Elsevier Science B.V.
All rights reserved.