SPECIATION OF METALS IN BIOMOLECULES BY USE OF INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRY WITH LOW AND HIGH-MASS RESOLUTION

Authors
JAKUBOWSKI N THOMAS C KLUEPPEL D STUEWER D
Citation
N. Jakubowski et al., SPECIATION OF METALS IN BIOMOLECULES BY USE OF INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRY WITH LOW AND HIGH-MASS RESOLUTION, Analusis, 26(6), 1998, pp. 37-43
Citations number
42
Categorie Soggetti
Chemistry Analytical
Journal title
Analusis → ACNP
ISSN journal
03654877
Volume
26
Issue
6
Year of publication
1998
Pages
37 - 43
Database
ISI
SICI code
0365-4877(1998)26:6<37:SOMIBB>2.0.ZU;2-U
Abstract
Speciation and metabolization of platinum and selenium in biological s ystems was investigated by HPLC coupled to low and high resolution ICP -MS. Using size exclusion chromatography more than 90% of the Pt found in a grass sample was present in an inorganic fraction while the rema ining 10% occurred in 4 different organic fractions. Selenium Was stud ied in sea-gull eggs by use of reversed-phase HPLC. Six separated Se-o rganic compounds were observed, the major compounds being selenocystin e and selenocystamine.