ANTIDIARRHEAL ACTIVITY OF C-9 ALDEHYDE ISOLATED FROM ALOYSIA-TRIPHYLLA

Citation
S. Perez et al., ANTIDIARRHEAL ACTIVITY OF C-9 ALDEHYDE ISOLATED FROM ALOYSIA-TRIPHYLLA, PTR. Phytotherapy research, 12, 1998, pp. 45-46
Citations number
6
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
12
Year of publication
1998
Supplement
1
Pages
45 - 46
Database
ISI
SICI code
0951-418X(1998)12:<45:AAOCAI>2.0.ZU;2-7
Abstract
C-9 aldehyde was found in Aloysia triphylla essential oil. It was test ed an diarrhoeic mice induced with castor oil or magnesium sulphate. I t was found that this compound diminished the number of diarrhoeic fae ces at doses of 7, 14 and 28 mu L. The highest effect was found with 1 4 mu L. Also, the effect of this compound was evaluated on the intesti nal transit of rats increased by castor oil. At the dose used, the int estinal transit was delayed in the first 30 min after adminstration of the cathartic agent. (C) 1998 John Wiley & Sons, Ltd.