CLINICAL MANAGEMENT OF IRON OVERLOAD

Hemochromatosis is characterized by iron accumulation in different sit es of the body, with subsequent organ toxicity In this article, the he patic and systemic consequences of iron overload are reviewed, with an emphasis on hereditary hemochromatosis. The clinical management of sy stemic iron overload is highlighted, with a special discussion of the role of newly available genetic testing in the diagnosis and family sc reening of hereditary hemochromatosis.