OXYPHILIC CELL VARIANT OF ENDOMETRIOID ADENOCARCINOMA

A case of oxyphilic cell Variant of endometrioid adenocarcinoma is pre sented. To the best of our knowledge, there have been only three such cases reported in the English literature. The patient was a 35-year-ol d Japanese female (gravida 0, para 0). She was slightly obese with pro fuse vaginal bleeding. Histological examination of the resected uterus revealed endometrioid adenocarcinoma with an exclusive oxyphilic cell component. There was no evidence of myometrial invasion nor lymph nod e metastases, Reported cases of oxyphilic cell variant of endometrioid adenocarcinoma, including the present case, were stages 0-I and grade s 1-2. Although further study is necessary to evaluate this variant, o xyphilic cell variant seems to be an early stage of adenocarcinoma and should be differentiated from eosinophilic metaplasia and other types of adenocarcinoma of the endometrium.