A CYCLOARTANE TRITERPENE 3-BETA, 16-BETA DIGLUCOSIDE FROM ASTRAGALUS-TRIGONUS AND ITS NON NATURAL 6-HYDROXY EPIMER

Authors
VEROTTA L ORSINI F TATO M ELSEBAKHY NA TOAIMA SM
Citation
L. Verotta et al., A CYCLOARTANE TRITERPENE 3-BETA, 16-BETA DIGLUCOSIDE FROM ASTRAGALUS-TRIGONUS AND ITS NON NATURAL 6-HYDROXY EPIMER, Phytochemistry, 49(3), 1998, pp. 845-852
Citations number
26
Categorie Soggetti
Biology,"Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
49
Issue
3
Year of publication
1998
Pages
845 - 852
Database
ISI
SICI code
0031-9422(1998)49:3<845:ACT31D>2.0.ZU;2-8
Abstract
The detailed investigation of Astralagus trigonus DC roots, led to the isolation of a new cycloartan-3 beta, 16 beta diglucoside, whose stru cture was elucidated by extensive use of 1D- and 2D- high field (600 M Hz) NMR techniques. The NaBH4 reduction of the natural 6-ore 3 beta, 1 6 beta diglucoside, previously isolated from the same plant, afforded the 6-epi-derivative of the new compound. The conformational preferenc e of both these compounds has been investigated by high field H-1 NMR spectroscopy and molecular modeling techniques. (C) 1998 Elsevier Scie nce Ltd. All rights reserved.