Riedel's invasive fibrous thyroiditis (IFT) is a rare disease of unkno
wn etiology characterized by a dense fibrosis involving the thyroid gl
and and its surrounding tissues. Clinically, patients present with a s
tony hard goiter frequently associated with compressive symptoms. Invo
lvement of the surrounding neck structures by IFT can lead to various
clinical sequelae. We report the case of a 55-year-old woman with know
n IFT who developed thrombosis in the right internal jugular vein that
progressed to the right sigmoid, transverse, and superior sagittal si
nuses. IFT could have predisposed to cerebral venous sinus thrombosis
by causing venous stasis, vascular damage and possibly a hypercoagulab
le state. To our knowledge, this is the first report of cerebral venou
s sinus thrombosis that developed as a complication of IFT.