COMPOUNDS WITH BRIDGEHEAD NITROGEN - PART 76 - THE STEREOCHEMISTRY OFPERHYDROCYCLOHEPTA[F]PYRIDO[1,2-C][1,3]OXAZEPINES AND CYCLOOCTA[F]PYRIDO[1,2-C][1,3]OXAZEPINES

Authors
CRABB TA ROCH OG WILSON SJ
Citation
Ta. Crabb et al., COMPOUNDS WITH BRIDGEHEAD NITROGEN - PART 76 - THE STEREOCHEMISTRY OFPERHYDROCYCLOHEPTA[F]PYRIDO[1,2-C][1,3]OXAZEPINES AND CYCLOOCTA[F]PYRIDO[1,2-C][1,3]OXAZEPINES, ACH, models in chemistry, 135(4), 1998, pp. 485-491
Citations number
6
Categorie Soggetti
Chemistry
Journal title
ACH, models in chemistry → ACNP
ISSN journal
12178969
Volume
135
Issue
4
Year of publication
1998
Pages
485 - 491
Database
ISI
SICI code
1217-8969(1998)135:4<485:CWBN-P>2.0.ZU;2-U
Abstract
Whereas syn-perhydrocyclohepta- and cycloocta[f]pyrido[1,2-c][1,3]oxaz epine preferentially adopt the trans-syn-trans- conformations (ca. 92 and 90 %, respectively, in CD2Cl2 at 183 K) the corresponding anti-iso mers prefer the cis-anti-trans-conformations (ca. 90 % and 75 %, respe ctively, in CD2Cl2 at 183 K).