Background: Rhabdomyosarcomas are rare, malignant tumors derived from
primitive myogenic precursors and are the most common soft tissue neop
lasms in children and adolescents. We used primary chemotherapy and su
bsequent removal of the residual polypoid mass to treat an adolescent
female with uterine rhabdomyosarcoma. Case: A 15-year-old white adoles
cent who presented with a polypoid uterine rhabdomyosarcoma was treate
d with vincristine, etopside, and ifosfamide, after which the residual
polypoid mass was removed. Conclusion: Treating adolescent females wi
th a polypoid uterine rhabdomyosarcoma with primary chemotherapy follo
wed by removal of the residual mass preserves reproductive function an
d should be considered. (Obstet Gynecol 1998;92:669-70. (C) 1998 by Th
e American College of Obstetricians and Gynecologists.)