Background: Burkitt lymphoma during pregnancy is a rare event, and out
comes have been poor. However, few patients were treated by current st
andards, with nearly half receiving single-agent cyclophosphamide or n
o chemotherapy. Case: A patient with Burkitt lymphoma presenting at 11
6/7 weeks' gestation was treated with surgical resection of all visib
le disease and cytotoxic combination chemotherapy. The patient was dis
ease free at 1 year after diagnosis. Conclusion: When Burkitt lymphoma
is encountered in pregnancy, immediate cytotoxic combination chemothe
rapy is indicated. (Obstet Gynecol 1998;92:675-8. (C) 1998 by The Amer
ican College of Obstetricians and Gynecologists.)