ISOLATION, STRUCTURE AND SYNTHESIS OF CHEVALIERIN-A, CHEVALIERIN-B AND CHEVALIERIN-C, CYCLIC-PEPTIDES FROM THE LATEX OF JATROPHA-CHEVALIERI

Authors
BARAGUEY C AUVINGUETTE C BLOND A CAVELIER F LEZENVEN F POUSSET JL BODO B
Citation
C. Baraguey et al., ISOLATION, STRUCTURE AND SYNTHESIS OF CHEVALIERIN-A, CHEVALIERIN-B AND CHEVALIERIN-C, CYCLIC-PEPTIDES FROM THE LATEX OF JATROPHA-CHEVALIERI, Journal of the Chemical Society. Perkin transactions. I (Print), (18), 1998, pp. 3033-3039
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I (Print) → ACNP
ISSN journal
0300922X
Issue
18
Year of publication
1998
Pages
3033 - 3039
Database
ISI
SICI code
0300-922X(1998):18<3033:ISASOC>2.0.ZU;2-U
Abstract
From the EtOAc extract of the latex of Jatropha chevalieri (Euphorbiac eae), two cyclooctapeptides, chevalierins A (1) and B (2), and a cyclo nonapeptide, chevalierin C (3), were isolated by a multi-step chromato graphy procedure, including HPLC, Their structures were elucidated by chemical degradation, mass spectrometry, homonuclear and heteronuclear NMR experiments and confirmed from their synthesis. Their antimalaria l activities were examined.